High Cholesterol

High cholesterol is a top-level condition because Paul observes lipid numbers rising during UC/proctitis flares and falling when symptoms are controlled.

Current UC/proctitis relevance

Canonical overlap page:

Current interpretation:

  • Paul’s cholesterol-rise-with-flare pattern is important, but it is not the default population-level IBD pattern.
  • A 2023 systematic review/meta-analysis found IBD patients generally had lower TC/LDL/HDL than controls, and active/non-mild disease tended to show lower lipids.
  • Therefore Paul’s pattern should be tracked as a personal-outlier clue and interpreted with fasting status, diet, weight, thyroid/metabolic markers, liver/bile markers, sleep, medications/supplements, and flare timing.

Buildout TODO

  • Import relevant Notion/Health Meetings notes.
  • Integrate Guava data when available.
  • Build personal lipid timeline with flare/remission status.
  • Track fasting status, diet, weight, sleep, thyroid/metabolic labs, medication/supplement changes.
  • Link to UC/proctitis where mechanisms overlap.
  • Add ApoB, LDL-P, Lp(a), hs-CRP, A1c/insulin, and liver markers if available.

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